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Lightstone Ventures

Lightstone Ventures

Menlo Park, Californialightstonevc.com

Overview

Lightstone Ventures is a global venture capital firm investing in biotech and medtech companies pioneering big ideas poised to transform patient outcomes . The firm empowers visionary entrepreneurs with the resources and operational guidance necessary to bring their innovative therapeutics and technologies to the patients who need them most . Lightstone seeks to identify and support innovative life science companies that have the potential to make a significant impact on human health . With a strong focus on working closely with their portfolio companies, Lightstone provides both financial support and strategic guidance to help these companies achieve their full potential .

Year Founded

2012

AUM

$850M

Portfolio Companies

30

Investments

Lightstone Ventures investments
CompanyDateStageLead
Crystalys TherapeuticsJul 2026Series BCo-investor
CerevanceMay 2026Series CCo-investor
PsiTheraDec 2025Series ALead
Alchemab TherapeuticsSep 2025Series A ExtensionCo-investor
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Key People

Mark Deem

Operating Partner

Caroline G.

Partner

Hanson Gifford

Partner

Ralph Christoffersen

Special Partner

Brendan Kelly

Principal

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Sector & Stage Mix

Industry, funding stage, and valuation band breakdowns.

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SeedSeries ASeries BGrowth

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Investment Activity

Yearly cadence, pace, and funding raised over time.

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2021
2022
2023
2024
2025
2026

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FAQ

Where is Lightstone Ventures based?

Lightstone Ventures is headquartered in Menlo Park, California, United States.

When was Lightstone Ventures founded?

Lightstone Ventures was founded in 2012.

How many portfolio companies does Lightstone Ventures have?

Lightstone Ventures has 30 portfolio companies in Caplight's dataset.

What are some companies in Lightstone Ventures's portfolio?

Recent investments visible on Caplight include Crystalys Therapeutics, Cerevance, PsiThera, Crystalys Therapeutics, Alchemab Therapeutics.

What was Lightstone Ventures's most recent investment?

Lightstone Ventures's most recent investment on Caplight was in Crystalys Therapeutics in 2026.

What sectors does Lightstone Ventures focus on?

Lightstone Ventures focuses on Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Healthcare & Life Sciences, Consumer & Commerce, Frontier & Industrial Tech, Consumer & Commerce, Enterprise Software, Frontier & Industrial Tech, AI, Data & Cloud Infrastructure, Enterprise Software.

What company stages does Lightstone Ventures focus on?

Lightstone Ventures typically invests at the MultiStage stage.

What is Lightstone Ventures's AUM?

Lightstone Ventures's assets under management are estimated between $500.0M and $1.0B.

Firmographic Details

HeadquartersMenlo Park, California
Year Founded2012
AUM$850M

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